Other reported clinical experience has not identified differences in responses between elderly and younger patients. Ammonium Lactate Lotion, 12% is available as follows: Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Ammonium Lactate Lotion 12%C-P , Fliptop - (400grams/14oz) - Pack of 2; Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube by Major Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube [2 PACK] AMMONIUM LACTATE 12% MOISTURIZING LOTION 226GM (8 OZ) EACH (PACK OF 2) *COMPARE TO THE SAME ACTIVE INGREDIENTS FOUND IN AMLACTIN & SAVE! Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. Less frequently occurring side effects include irritation, dryness, eczema, changes in skin color, or small … Apply to the affected areas and rub in thoroughly. Usual Dosage: Shake well. It is a moisturizer that is designed to treat the symptoms of dry, scaly skin conditions such as ichthyosis vulgaris and xerosis. Clinical studies of Ammonium Lactate lotion, 12% did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Keep your skin looking smooth, vibrant and healthy with this Ammonium Lactate 12 Percent Cream. August 22, 2012 at 2:36 pm Ammonium lactate is commonly sold over the counter by the name of amlactin, LAC lotion, or LAC hydrin. Other reported clinical experience has not identified differences in responses between elderly and younger patients. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. It is usually applied to the affected skin area twice daily. Due to the more severe initial skin conditions associated with ichthyosis, there was a higher incidence of transient stinging, burning and erythema (each occurring in 1 in 10 patients). Animal reproduction studies have been performed in rats and rabbits at doses up to 0.7 and 1.5 times the human dose, respectively (600 mg/kg/day, corresponding to 3600 mg/m2/day in the rat and 7200 mg/m2/day in the rabbit) and have revealed no evidence of impaired fertility or harm to the fetus due to ammonium lactate formulations. Not for Ophthalmic, Oral or Intravaginal Use. Ammonium lactate also prevents keratinization of epidermal skin layer, which keeps skin smoother and hydrated for a longer time. Do not use in larger or smaller amounts or for longer than recommended. Distributed By Perrigo, Allegan, MI 49010. Use twice daily or as directed by a physician. *Ammonium Lactate Lotion, 12% specially formulates 12% lactic acid neutralized with ammonium hydroxide, as ammonium lactate to provide a lotion pH of 4.5 - 5.5. Sadly, a small percentage of you may experience a negative reaction to the lotion. Ammonium lactate comes as a cream and a lotion to apply to the skin. Sun exposure (natural or artificial sunlight) to areas of the skin treated with Ammonium Lactate Lotion, 12% should be minimized or avoided (see PRECAUTIONS). imprint No data. However, a long-term photocarcinogenicity study in hairless albino mice suggested that topically applied 12% ammonium lactate formulations enhanced the rate of ultraviolet light-induced skin tumor formation. *Ammonium Lactate Lotion, 12% specially formulates 12% lactic acid neutralized with ammonium hydroxide, as Ammonium Lactate to provide a lotion pH of 4.5 - 5.5. In general, dose selection for an elderly patient should be cautious. Set id: dc3a6462-0f2c-4306-b5ef-c7b47395e959, Not for Ophthalmic, Oral or Intravaginal Use, 225 g in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product, 400 g in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product. The oral administration of ammonium lactate to rats and mice showed this drug to be practically non-toxic (LD50>15 mL/kg). I've been using it for years, including back when it was only available by prescription here. Select one or more newsletters to continue. Ammonium Lactate Lotion, 12% is contraindicated in those patients with a history of hypersensitivity to any of the label ingredients. The following image is a placeholder representing the product identifier that is either affixed or imprinted on the drug package label during the packaging operation. Apply to the affected areas and rub in thoroughly. Use twice daily or as directed by a physician. The use of Ammonium Lactate Lotion, 12% should be discontinued if any hypersensitivity is observed. CONTAINS: *Ammonium lactate equivalent to 12% lactic acid, cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Animal reproduction studies have been performed in rats and rabbits at doses up to 0.7 and 1.5 times the human dose, respectively (600 mg/kg/day, corresponding to 3600 mg/m2/day in the rat and 7200 mg/m2/day in the rabbit) and have revealed no evidence of impaired fertility or harm to the fetus due to Ammonium Lactate formulations. Because many drugs are excreted in human milk, caution should be exercised when ammonium lactate is administered to a nursing woman. color white shape No data. Any ammonium lactate lotion will have this smell - I have used several brands with success. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. The most frequent side effect of using topical 12 percent ammonium lactate lotion is a stinging or burning sensation. The mutagenic potential of ammonium lactate formulations was evaluated in the Ames assay and in the mouse in vivo micronucleus assay, both of which were negative. ➺ Common brand names: Lac-Hydrin, AmLactin, Geri-Hydrolac, LAClotion, LAC Cream, Al-12 ➺ Generic name: ammonium lactate ➺ Drug class and mechanism: It is an anti-itch prescription medicine. Use twice daily or as directed by a physician. Many lotions and creams sting terribly and cause worse suffering, but Ammonium Lactate cream is so cooling and soothing and does not further irritate my sensitive skin. ammonium lactate 12 % lotion. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. For external use only. Apply to the affected areas and rub in thoroughly. Available for Android and iOS devices. An in vitro study of percutaneous absorption of Ammonium Lactate lotion, 12% using human cadaver skin indicates that approximately 5.8% of the material was absorbed after 68 hours. Ammonium lactate is an anti- itch topical medication formulated from 12% lactic acid and ammonium hydroxide. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. Although lactic acid is a normal constituent of blood and tissues, it is not known to what extent this drug affects normal lactic acid levels in human milk. There are, however, no adequate and well-controlled studies in pregnant women. Ammonium Lactate Cream, 12% also contains cetyl alcohol, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Lotions are thinner and lighter in consistency and can be used all over the body (for example, in case of eczema). Although lactic acid is a normal constituent of blood and tissues, it is not known to what extent this drug affects normal lactic acid levels in human milk. Medically reviewed by Drugs.com. ➺ It is available in the form of cream as well as lotion. Lactic acid is a racemic mixture of 2-hydroxypropanoic acid and has the following structural formula: Lactic acid is an alpha-hydroxy acid, it is a normal constituent of tissues and blood. * by AmLactin Ammonium Lactate; Third Edition Patients using Ammonium Lactate Lotion, 12% should receive the following information and instructions: The topical treatment of CD-1 mice with 12%, 21% or 30% ammonium lactate formulations for two-years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. Shake well. This property may influence hydration of the stratum corneum. Ammonium Lactate Lotion, 12% is available as follows: Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. Rash and peeling skin may also occur. Perrigo New York Inc, For Dermatologic Use Only Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. I have been given Lac Hydrin over the years but I hate it because it stings badly if any of your skin is irritated or cracked. The mechanism(s) by which this is accomplished is not yet known. Because animal reproduction studies are not always predictive of human response, Ammonium Lactate Lotion, 12% should be used during pregnancy only if clearly needed. The mutagenic potential of Ammonium Lactate formulations was evaluated in the Ames assay and in the mouse in vivo micronucleus assay, both of which were negative. Use twice daily or as directed by a physician. The following image is a placeholder representing the product identifier that is either affixed or imprinted on the drug package label during the packaging operation. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. Ammonium Lactate Lotion, 12% is contraindicated in those patients with a history of hypersensitivity to any of the label ingredients. Shake the lotion form of this medication well just before using it. Stinging or burning may occur when applied to skin with fissures, erosions, or that is otherwise abraded (for example, after shaving the legs). This is a serious creme that provides incredible relief and promotes healing, but it is not a quick-absorb lotion so one will need gloves to help with absorption. Stinging or burning may occur when applied to skin with fissures, erosions, or that is otherwise abraded (for example, after shaving the legs). The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. An in vitro study of percutaneous absorption of ammonium lactate lotion, 12% using human cadaver skin indicates that approximately 5.8% of the material was absorbed after 68 hours. Not for Ophthalmic, Oral or Intravaginal Use. The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. Distributed By Perrigo, Allegan, MI 49010. Other adverse reactions which occur less frequently are irritation, eczema, petechiae, dryness, and hyperpigmentation. For lot number and expiration date, see bottle. The potential for post-inflammatory hypo- or hyperpigmentation has not been studied. Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube [2 PACK] AMMONIUM LACTATE 12% MOISTURIZING LOTION 226GM (8 OZ) EACH (PACK OF 2) *COMPARE TO THE SAME ACTIVE INGREDIENTS FOUND IN AMLACTIN & SAVE! Ammonium lactate is usually applied twice a day. Because many drugs are excreted in human milk, caution should be exercised when Ammonium Lactate is administered to a nursing woman. I think soaking is … Clinical studies of ammonium lactate lotion, 12% did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. … Lactic acid is an alpha-hydroxy acid. In dermal Segment I and III studies with ammonium lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m2/day), approximately 0.4 times the human topical dose. Because animal reproduction studies are not always predictive of human response, Ammonium Lactate Lotion, 12% should be used during pregnancy only if clearly needed. There are, however, no adequate and well-controlled studies in pregnant women. For external use only. I use it on hands, feet, knees. It is a normal constituent of tissues and blood. This medicine is a white, lotion ‹ Back to Gallery. Not for Ophthalmic, Oral or Intravaginal Use, We comply with the HONcode standard for trustworthy health information -, Lactic Acid and Ammonium Hydroxide Lotion. hydroxyzine, hydrocortisone topical, lidocaine topical, diphenhydramine, Benadryl, Eucerin, Aquaphor, AmLactin, dimethicone topical, CeraVe. Apply ammonium lactate at around the same time (s) every day. Amlactin Daily Moisturizing Body Lotion 12% at Walgreens. It also contains cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Usual Dosage: Shake well. Caution is advised when used on the face because of the potential for irritation. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. This topical medication is made from 12% lactic acid and ammonium hydroxide. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. This Ammonium Lactate cream infuses skin with moisture and smooths it out to give it a younger and healthier appearance. It also contains cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Patients using Ammonium Lactate Lotion, 12% should receive the following information and instructions: The topical treatment of CD-1 mice with 12%, 21% or 30% Ammonium Lactate formulations for two-years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. Apply to the affected areas and rub in thoroughly. * by AmLactin Ammonium Lactate… This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. CONTAINS: *Ammonium Lactate equivalent to 12% lactic acid, cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. This property may influence hydration of the stratum corneum. The oral administration of Ammonium Lactate to rats and mice showed this drug to be practically non-toxic (LD50>15 mL/kg). The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. For lot number and expiration date, see bottle. For Dermatologic Use Only Safety and effectiveness of Ammonium Lactate have been demonstrated in infants and children. The use of Ammonium Lactate Lotion, 12% should be discontinued if any hypersensitivity is observed. Other adverse reactions which occur less frequently are irritation, eczema, petechiae, dryness, and hyperpigmentation. Ammonium lactate hydrates the outermost skin layer and promotes skin moisturizing for a prolonged time. Safety and effectiveness of ammonium lactate have been demonstrated in infants and children. AMMONIUM LACTATE- ammonium lactate lotion  The alpha-hydroxy acids (and their salts) may act as … In general, dose selection for an elderly patient should be cautious. ammonium lactate 12 % topical cream. Get free shipping at $35 and view promotions and reviews for Amlactin Daily Moisturizing Body Lotion 12% The potential for post-inflammatory hypo- or hyperpigmentation has not been studied. ➺ Ammonium lactate cream is available in 280 grams (two 140 gram… No unusual toxic effects were reported. But the smell dissipates, and for many, it truly helps heal dry skin. Lac-Hydrin specially formulates 12% lactic acid, neutralized with ammonium hydroxide, as ammonium lactate to provide a lotion pH of 4.4-5.5. Due to the more severe initial skin conditions associated with ichthyosis, there was a higher incidence of transient stinging, burning and erythema (each occurring in 1 in 10 patients). Use exactly as directed on the label, or as prescribed by your doctor. and Milwaukee, Wisconsin A double-blind, paired comparison study was used to evaluate treatment effects of 12% ammonium lactate lotion (Lac-Hydrin) against its … However, a long-term photocarcinogenicity study in hairless albino mice suggested that topically applied 12% Ammonium Lactate formulations enhanced the rate of ultraviolet light-induced skin tumor formation. The mechanism(s) by which this is accomplished is not yet known. No unusual toxic effects were reported. Shake well. Evaluation of ammonium lactate in the treatment of seborrheic keratoses Maria V. Klaus, MD,a Richard F. Wehr, BS,b Roy S. Rogers III, MD,c Thomas J. Russell, MD: and Lincoln Krochmal, MOb Buffalo, New York, Rochester, Minnesota. Last updated on Sep 21, 2020. In dermal Segment I and III studies with Ammonium Lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m2/day), approximately 0.4 times the human topical dose. Lactic acid is a racemic mixture of 2-hydroxypropanoic acid and has the following structural formula: Lactic acid is an alpha-hydroxy acid, it is a normal constituent of tissues and blood. Caution is advised when used on the face because of the potential for irritation. Sun exposure (natural or artificial sunlight) to areas of the skin treated with Ammonium Lactate Lotion, 12% should be minimized or avoided (see PRECAUTIONS). 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